•  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
期刊检索


检索
检索项:
检索词:
总目录
  • WCSB9︱2019(第九届)世界采样和混样大会 查看全文>>
  • 关于召开第十五届全国青年分析测试学术报告会的通知 查看全文>>
友情链接
QuEChERS/高效液相色谱-串联质谱法测定土壤中61种激素类药物残留
    点此下载全文
作者单位
任雪冬,王璐,熊爽 辽宁省分析科学研究院 
基金项目:辽宁省自然科学基金计划重点项目(20170540479,20180551192)
中文摘要:建立了QuEChERS/高效液相色谱-串联质谱(HPLC-MS/MS)测定土壤中61种激素类药物残留的分析方法。样品经乙腈提取,QuEChERS方法净化后进行HPLC-MS/MS测定。采用电喷雾离子源(ESI),正、负模式扫描,多反应监测(MRM)模式采集,基质匹配工作曲线法定量。结果表明:61种目标化合物在各自浓度范围内线性良好,相关系数(r2)为0.991 8~0.999 8,检出限(LOD,S/N≥3)为0.01~2.3 μg/kg,定量下限(LOQ,S/N≥10)为0.03~7.5 μg/kg;在10、50、200 μg/kg 3个加标水平下,平均回收率为62.6%~102%,相对标准偏差(n=6)为1.0%~11%。该方法简单、快速、重现性好、稳定性高,可满足土壤中61种激素类药物残留的检测要求。
中文关键词:高效液相色谱-串联质谱(HPLC-MS/MS)  QuEChERS  激素残留  土壤
 
Determination of 61 Hormone Residues in Soil by QuEChERS/High Performance Liquid Chromatography-Tandem Mass Spectrometry
Abstract:A QuEChERS/high performance liquid chromatography-tandem mass spectrometric(HPLC-MS/MS)method was developed for the determination of 61 kinds of hormone residues in soil.Samples were extracted with acetonitrile,and then purified using QuEChERS method.Analysis on the targets was performed by electrospray ionization mass spectrometry in positive or negative mode,multiple reaction monitoring(MRM) mode was used for collection,and matrix matched standard curve method was selected for quantitation.Results showed that 61 analytes showed good linearities in their respective ranges,with correlation coefficients(r2) between 0.991 8 and 0.999 8.The limits of detection(LOD,S/N≥3) were 0.01-2.3 μg/kg while the limits of quantitation(LOQ,S/N≥10) were 0.03-7.5 μg/kg.Recoveries for the target analytes at spiked levels of 10,50 and 200 μg/kg ranged from 62.6% to 102%,with relative standard deviations(n=6) of 1.0%-11%.The method is simple,rapid,replicable and high stable,and could meet the requirements for determination of 61 hormone residues in soil.
Key Words:high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)  QuEChERS  hormone residues  soil
引用本文:任雪冬,王璐,熊爽.QuEChERS/高效液相色谱-串联质谱法测定土壤中61种激素类药物残留[J].分析测试学报,2019,(9):1036-1043.
摘要点击次数: 574
全文下载次数: 1555
查看全文  查看/发表评论  下载PDF阅读器