| 基于胸腺嘧啶碱基错配的汞离子传感器研究进展 |
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| 基金项目:湖北省教育厅科学技术研究项目(Q20181321）；大学生创新项目(2018141,2019289） |
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| 中文摘要:基于汞离子和胸腺嘧啶的质子取代反应，可形成T-Hg(Ⅱ）-T碱基错配结构，该结构可作为新型汞离子传感器的良好识别元件。相较于传统汞离子检测方法在效率与精度上的不足，以T-Hg(Ⅱ）-T碱基错配结构为识别基团的新型汞离子传感器具有一定优势。该文综述了以T-Hg(Ⅱ）-T结构为识别基团，以不同类型报告基团为基础的汞离子传感器的研究进展与趋势，从而为后续汞离子传感器的开发提供参考。 |
| 中文关键词:汞离子传感器 T-Hg(Ⅱ）-T结构 识别基团 报告基团 |
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| Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch |
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| Abstract:A T-Hg(Ⅱ）-T structure with base mismatch was formed based on the proton-substitution reaction between mercury ions and thymine,which could be used as a good recognition component for novel mercury ion sensors.Compared with the traditional detection methods,the new mercury ion sensors with T-Hg(Ⅱ）-T mismatch structure as recognizer had some advantages in efficiency and precision.In this paper,research progress and trend of this mercury ion sensors with T-Hg(Ⅱ）-T structure as recognizer based on different types of reporter groups were summarized,thus providing a reference for the development of mercury ion sensors. |
| Key Words:mercury ion sensor T-Hg(Ⅱ）-T structure recognition group reporter group |
| 引用本文：王久军，吴亚，马博文，张兴平.基于胸腺嘧啶碱基错配的汞离子传感器研究进展[J].分析测试学报,2020,39(6):814-820. |
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