| 生物样品中γ-羟基丁酸的检验方法与阈值研究 |
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| 基金项目:中央级公益性科研院所基本科研业务费项目(2020JB002) |
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| 中文摘要:γ-羟基丁酸是一种内源性物质，自20世纪60年代开始在临床中使用，由于其娱乐滥用性受到人们的广泛关注。该文介绍了γ-羟基丁酸的性质与应用、体内代谢和转化，综述了生物样品中γ-羟基丁酸的前处理和检测方法，以及体内γ-羟基丁酸阈值的最新研究进展，以期为法庭科学领域侦破相关案件提供参考和借鉴。 |
| 中文关键词:γ-羟基丁酸 检验方法 阈值研究 综述 |
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| Research on Detection Methods and Cut-off Values of γ-Hydroxybutyric Acid in Biological Samples |
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| Abstract:γ-Hydroxybutyric acid is an endogenous substance,which has been used in clinical practice since the 1960s,and has attracted extensive attention due to its recreational misuse.In this paper,the metabolism and transformation in vivo,properties and applications of γ-hydroxybutyric acid have been carried on the simple overview.In addition,the recent development of research in pretreatments and analysis methods for determination of GHB in biological samples has been reviewed in details, as well as the latest research progress of cut off values of γ-hydroxybutyric acid in vivo,in order to provide a reference or model for forensic science field to deal with related cases. |
| Key Words:γ-hydroxybutyrate(GHB) detection methods cut-off values research review |
| 引用本文：李润康,何洪源,李佳宜,张云峰,任昕昕.生物样品中γ-羟基丁酸的检验方法与阈值研究[J].分析测试学报,2021,40(4):488-494. |
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