| 化妆品分析样品前处理方法的研究进展 |
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| 基金项目:国家自然科学基金项目（21874159，21976213）；国家自然科学基金重点项目（22134007）；广东省药品监督管理局科技创新团队项目（2023TDZ10） |
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| 中文摘要:化妆品的广泛使用使其安全性问题受到关注。作为发现安全性问题的首要选择，分析检测技术十分重要。化妆品种类繁多、基质复杂，其样品前处理成为分析检测过程的关键所在。传统样品前处理方法因试剂消耗大、耗时、步骤繁琐等缺点无法满足绿色高效的检测要求，因此发展新的样品前处理技术具有重要意义。该文综述了近5年化妆品分析样品前处理方法及其应用，主要包括相分离方法、场辅助方法和衍生化方法等，并展望了其发展方向。 |
| 中文关键词:样品前处理 化妆品 分析检测 研究进展 |
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| Research Progress in Sample Pretreatment Methods for Cosmetic Samples Analysis |
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| Abstract:The widespread use of cosmetic products at home and abroad makes its safety problem attract extensive attention．As the first choice to find out the safety problem of cosmetic samples，analysis and detection technology is very important．Various morphology and complex matrix which cosmetic samples are characterized by bring great challenges to the detection of target analytes in cosmetics．Traditional sample pretreatment methods cannot meet the requirements for green and efficient detection due to the disadvantages of large reagent and time consumption，tedious preparation steps，etc．Therefore，it is of great significance to promote the rapid development of new sample pretreatment methods．An overview on the sample pretreatment methods for cosmetic samples analysis in the past five years is provided in this paper．The sample pretreatment methods which are placed special emphasis on in this review are phase separation methods，mainly including solid phase extraction，solid phase microextraction and liquid phase microextraction，field assisted methods including ultrasound-assisted，microwave-assisted and vortex-assisted extraction，and derivatization methods including post-column and pre-column derivatization．These techniques are used in a vast range of modern extraction process，which are of increasing interest．Finally，the prospect of the development direction of sample pretreatments for cosmetics samples analysis are also put forward. |
| Key Words:sample preparation cosmetic analytical determination research progress |
| 引用本文：尹林华，肖小华，霍冰洋，李攻科.化妆品分析样品前处理方法的研究进展[J].分析测试学报,2023,(5):647-656. |
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