Determination of Hexabromocyclododecane in Food Contact Materials by Liquid Chromatography Tandem Mass Spectrometry
  
View Full Text    Download reader
DOI:10.3969/j.issn.1004-4957.年份.月份
KeyWord:food contact materials  hexabromocyclododecane  liquid chromatography tandem mass spectrometry
  
AuthorInstitution
马强,李文涛,孙慧媛,于红梅,李晶瑞,孟宪双,白桦,王星,王超 中国检验检疫科学研究院
Hits: 3835
Download times: 1840
Abstract:
      A comprehensive analytical method based on liquid chromatography-tandem mass spectrometry was developed for the determination of α,β,γ-hexabromocyclododecane in polymer food contact materials.The samples were ultrasonically extracted with acetone as extraction solvent.The extract was cleaned up with ENVI-Carb Ⅱ/PSA solid phase extraction cartridge.The separation of the analyte was performed on a Waters XBridge C18 (150 mm×2.1 mm,3.5 μm) column using methanol-acetonitrile-water(41∶41∶18) as mobile phase by isobaric elution.The qualitative and quantitative analysis of the analyte were carried out under the multiple reaction monitoring(MRM) mode.The limits of quantitation(LOQs) for α,β,γ-hexabromocyclododecane were all 40 μg/kg.The mean recoveries at three spiked levels of 40.0-160.0 μg/kg were in the range of 86%-91%,with relative standard deviations(RSDs) of 1.9%-4.7%.The method was accurate,rapid and sensitive and was applicable to the inspection of hexabromocyclododecane in food contact materials.
Close