| A simple method based on SPE coupled with HPLC-MS/MS was developed for the determination of 1H-benzotriazole(BTri),5-methyl-1H-benzotriazole(5-TTri),5,6-dimethyl-1H-benzotriazole(5,6-DMBTri),5-chloro-1H-benzotriazole(5-ClBTri),1-hydroxybenzotriazole(1-OHBTri),benzothiazole(BT),2-aminobenzothiazole(2-ABT) and 2-methylbenzothiazole(2-TBT) in surface water.Extraction and cleanup of surface water samples were performed on an HLB solid-phase extraction cartridge.The optimum extraction process was as follows:pH value of sample:3.0,sampling volume:200 mL,washing solvent:3 mL 10% methanol,eluting solvent:6 mL 20% acetone in methanol.Separation of target compounds was achieved on a Hypersil GOLD analytical column(150 mm×2.1 mm) with methanol-acetonitrile-water as mobile phase by gradient elution.Quantitative analysis by ESI-MS/MS was achieved using positive ion mode with multiple reaction monitoring mode.The calibration curves were linear in the range of 8-1 000 μg/L for 1-OHBTri,BT and 2-TBT,and 1.6-1 000 μg/L for rest of the compounds,with correlation coefficients more than 0.99.The average recoveries of target compounds were in the range of 59.8%-98.7% with relative standard deviations(RSDs,n=5) of 0.9%-12.5%.The instrumental limits of detection(S/N=3) for eight target compounds were in the range of 0.03-1.4 μg/L。 |