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| Application of Microfluidic Chip in the Research of Sperm Cell |
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| DOI：10.3969/j.issn.1004-4957.年份.月份 |
| KeyWord:microfluidic chip sperm cell culturing sorting intracellular contents analysis in-vitro fertilization（IVF） |
| Author | Institution |
| YANG Hui,YANG Fan*,CAO Ji-gang*,CHEN Zuan-guang |
1.河南科技大学医学院;2.湖北中医药大学检验学院; 3.湖北中医药大学基础医学院;4.中山大学药学院 |
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| Abstract: |
| With the sophistication and variety of microchannels,microfluidic chip which is integrated with multifunctional units including cell loading,culturing,sorting,lysis,separation and detection,not only matches sperm cells in size,but also supplies them with relatively closed growing microenvironments close to physiological level.Some investigations on sperm based on laminar flow and special microchannel geometry were studied.In this paper,the applications of microfluidic chip systems in sperm cell culturing,sorting,intracellular contents analysis and in-vitro fertilization（IVF） were reviewed.Several microfluidic chip systems used to study sperm cell were introduced.Varied sorting methods on sperm cell were also discussed. |
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