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| Synthesis of Porous Porphyrin Compound and Its Application in Photoelectric Immunosensor |
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| DOI： |
| KeyWord:porphyrin porous materials photoelectric immunosensor C-reactive protein application |
| Author | Institution |
| WANG Min,MENG Shuang,GU Meng-qiao,CHI Kuan-neng,MA Yu-chan,DENG Yan,LI De-lei,ZHANG Xi,HU Rong,YANG Yun-hui |
College of Chemistry and Chemical Engineering,Yunnan Normal University |
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| Abstract: |
| In this paper,a label free C-reactive protein（CRP）photoelectricimmunosensor was constructed using porous porphyrin compound-Au nanoparticles（Au NPs@PAF）as an immobilized substrate.Under the optimal conditions,the CRP was quantitatively detected by chronograph current method.There was a good linear relationship for the sensor versus photocurrent in the range of 0.05-60 ng/mL,with a linear correlation coefficient of 0.994 6.The limit of detection was 0.017 ng/mL,and the average recovery was 102%.This sensor provided a sensitive method for the detection of C-reactive protein with good selectivity. |
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