Research Progress on High Performance Liquid Chromatography in Analysis and Preparation of Alkaloids
  
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KeyWord:alkaloids  peak tailing  preparative HPLC  orthogonal separation
  
AuthorInstitution
WANG Rong,LIU Yan-fang,WANG Chao-ran,GUO Zhi-mou,LIANG Xin-miao 1.Key Lab of Separation Science for Analytical Chemistry,Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian,China;2.University of Chinese Academy of Sciences
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Abstract:
      Alkaloids are a class of natural compounds with good pharmacological properties.In the field of separation science and technology,alkaloid separation has always been a hot and difficult problem.In recent years,with the development of high performance liquid chromatography(HPLC) materials and separation methods,great progresses in alkaloid analysis and preparation have been achieved.In this article,the theoretical development and technological advances with respect to peak tailing problems of basic compounds are summarized,and the applications of HPLC in natural alkaloid analysis and preparation are discussed.The further development of HPLC separation on alkaloids is also looked forward.
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