Research Advance in Detection of Ochratoxin A Based on Electrochemical Sensors
  
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KeyWord:ochratoxin A(OTA)  electrochemical sensing  research advance
  
AuthorInstitution
LI Lin-zhi,HE Sai-jun,HUANG Tian-zeng,LIU Xing,CHEN Qi,CHEN Jian,CAO Hong-mei 1.College of Food Science and Technology,Hainan University,Haikou,China;2.College of Chemistry and Engineering Technology,Hainan University,Haikou,China;3.Key Laboratory of Food Nutrition and Functional Food of Hainan Province,Haikou,China;4.Engineering Research Center of Utilization of Tropical Polysaccharide Resources,Haikou,China;5.Hainan Provincial Engineering Research Center of Aquatic Resources Efficient Utilization in the South China Sea,Haikou,China
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Abstract:
      Ochratoxin A(OTA) is a secondary metabolite originated from fungi penicillium and aspergillus,which is widely distributed in nature,with various strong toxicities such as hepatotoxicity,nephrotoxicity,carcinogenic and mutagenic effects.Considering these potential toxic effects of OTA,the International Agency for Research on Cancer(IARC) has classified it as a human carcinogen(Ⅱ B).Therefore,how to develop OTA detection methods with high sensitivity have arouse wide attention.The development and applications of electrochemical sensors for OTA detection for the past 10 years are summarized in this paper.Based on different identification elements,the main types of OTA electrochemical sensors,adaptor and immune sensing,and the advantages and disadvantages of the corresponding sensings are described.The prospect for the future development of OTA electrochemical sensors is put forward.This review provides a certain reference for the further research and application of OTA electrochemical sensors.
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