|
| Recent Progress of Proteomics-driven Precision Medicine |
| |
| View Full Text Download reader |
| DOI： |
| KeyWord:proteomics ?mass spectrometry ?biomarker ?proteomics-driven precision medicine（PDPM） |
| Author | Institution |
| ZHANG Lei，WANG Xiao-yu，ZHANG Ying，LU Hao-jie |
1. Institutes of Biomedical Sciences，Fudan University，Shanghai ，China;2. NHC Key Laboratory of Glycoconjugates Research，Fudan University，Shanghai ，China |
|
| Hits: 1023 |
| Download times: 383 |
| Abstract: |
| Proteins involve in virtually all cell functions and participate in a variety of metabolic and physiological processes．Proteomics，which systematically analyzes the protein expression levels，modification states of proteins，and intracellular protein-protein interactions，provides a global perspective on how these molecules changes at different stages of disease occurrence and development．Recently，clinical proteomics has been proven to play a significant role in early diagnosis，prognosis，and monitoring of disease development．The concept of proteomics-driven precision medicine has been proposed thereby．In this review，the progress of proteomics-driven precision medicine（PDPM） and its application in the studies of major diseases are summarized. |
| Close |