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| Immobilization Methods of Bioreceptor for Surface Plasma Resonance Sensors |
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| DOI： |
| KeyWord:surface plasma resonance sensors bioreceptor immobilization |
| Author | Institution |
| WAN Hong，ZHAO Zhao，LIANG Hua-lei，CUI Hai-rong，LIU Hu-wei |
School of Life Science，Wuchang University of Technology，Wuhan ，China |
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| Abstract: |
| Surface plasma resonance is widely used for drug screening，and the analysis in biological，pharmaceutical，food and other fields due to its advantages of no labeling and real-time detection．Constructing a suitable biosensing interface is an important way to improve the detection sensitivity and selectivity of biosensors．This review describes the non-oriented immobilization methods using chemically coupled bioreceptor and the oriented immobilization methods that utilize specific properties of chemical bonding or biomolecules．The advantages and disadvantages of each immobilization method are summarized，and the future development is also discussed. |
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