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| Determination of Venlafaxine Using Ag（Ⅲ） Complex-Luminol Chemiluminescence System |
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| DOI：10.3969/j.issn.1004-4957.年份.月份 |
| KeyWord:venlafaxine luminol Ag（Ⅲ） complex flow injection chemiluminescence（CL） |
| Author | Institution |
| 苑洁，王玮,康维钧，徐向东 |
河北医科大学公共卫生学院 |
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| Abstract: |
| Based on the fact that venlafaxine had remarkable enhancing effect on Ag（Ⅲ） complex-luminol chemiluminescence（CL） system，a novel method for the determination of venlafaxine was established by CL method with flow-injection analysis.Under the optimum conditions，the calibration curve was linear in the range of 0.1-2.0 mg?L-1 with detection limit（S/N=3） of 0.05 mg?L-1.The relative standard deviation（n=11） for 0.1 mg?L-1 venlafaxine was 0.87%，and the recovery ranged from 96% to 105%.This method was simple，sensitive and accurate，and was successfully applied in the determination of venlafaxine in capsules. |
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