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| Determination of Folic Acid Using Mn2+ Doped ZnS Quantum Dots Capped with L-Cysteine |
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| DOI：10.3969/j.issn.1004-4957.年份.月份 |
| KeyWord:folic acid Mn-doped ZnS quantum dots fluorescence determination L-cysteine |
| Author | Institution |
| 占浔寿，商燕，吴芳英 |
南昌大学化学系 |
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| Abstract: |
| Water soluble L cysteine modified ZnS∶Mn2+ quantum dots（QDs） were prepared in aqueous solution under the room temperature,and characterized by infrared spectrometry,ultraviolet-visible spectrometry,fluorescence spectrometry and X-ray diffraction spectrometry.Based on the fluorescence quenching of ZnS∶Mn2+ QDs caused by folic acid（FA） ,the prepared QDs were evaluated as a fluorescence probe for FA detection.Factors affecting the fluorescence detection on FA were studied.Under the optimal conditions,the quenched fluorescence intensity was linear with FA concentration in the range of 1.0×10-6-7.0×10-5 mol?L-1 with correlation coefficient of 0.994.The limit of detection for FA was 9.6×10-7 mol?L-1.The proposed method was applied in the determination of folic acid in folic acid tablet and urine samples with satisfactory results.The mechanism for detection of FA was also investigated. |
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