Nanoparticle-based Colorimetric Sensing Assay and Its Applications in Chemical and Biological Detections
  
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DOI:10.3969/j.issn.1004-4957.年份.月份
KeyWord:nanoparticles  colorimetric  heavy metal ions  biomolecules  chemical sensing  biological detection  review
  
AuthorInstitution
周化岚,翟莲娜,缪煜清,黎莹,施文健 1.上海理工大学环境与建筑学院;2.浙江师范大学化学与生命科学学院
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Abstract:
      Nanoparticle-based colorimetric sensing assays have recently attracted considerable attention in diagnostic application due to their simplicity and versatility.The key to establish nanoparticle-based colorimetric sensing assay is the control of nanoparticle dispersion and aggregation by using analytes of interest.Consequently,the color of the solution is the central in the design of such systems.This paper introduced briefly the physical phenomenon (i.e.colors) associated with nanoparticles and their aggregation, discussed the interparticle forces of nanoparticles,and described the modulation of nanoparticle stability and aggregation,which utilized both interparticle crosslinking and noncrosslinking aggregation mechanisms.The applications of nanoparticle-based colorimetric sensing assay in detecting heavy metal ions and biomolecules were reviewed,and its prospect was put forward.
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