| A rapid analytical method based on solid phase extraction and ultra performance liquid chromatography（UPLC) was developed for the determination of 9 kinds of bisphenol diglycidyl ethers,including bisphenol A diglycidyl ether(BADGE) and its derivatives:BADGE?2H2O,BADGE?H2O,BADGE?2HCl,BADGE?HCl,BADGE?H2O?HCl,bisphenol F diglycidyl ether(BFDGE) and its derivatives:BFDGE?2H2O and BFDGE?H2O.The beverage samples were extracted twice by votex shaking with methyl tert-butyl ether.The extract was dried by a relax flow of nitrogen at 40 ℃.The residue was redissolved with methanol-water(2∶3) followed by cleaning up using PLS solid phase extraction.The target compounds were separated on a Shim-pack XR-ODS-Ⅲ column by gradient elution using acetonitrile - water as mobile phase.Under the optimized conditions,the calibration curves showed good linearity in the range of 0.05-10 mg/L.The recoveries at two spiked concentration levels ranged from 83.8% to 98.7%，with RSDs of 2.3%-5.6%.The limits of detection(LODs) for the target compounds were all 20 μg/kg.The method is sensitive and simple,and is suitable for the rapid determination of 9 kinds of bisphenol diglycidyl ethers in 10 min. |