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| Progress on Application of Different Selective Reagents in Counter-current Chromatography |
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| DOI： |
| KeyWord:Counter-current chromatography selective reagent fundamental principle review |
| Author | Institution |
| LU Meng-xia,XIONG Qing,WANG Xiao-ping,YAN Ji-zhong,TONG Sheng-qiang* |
浙江工业大学药学院 |
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| Abstract: |
| Using selective reagents in the separation technique of complexation counter-current chromatography can improve the resolution effectively.The commonly used selective reagents include metal ion selective reagent,polysaccharideion selective reagent,anionic surface active agent,ion pair selective reagent,chiral reagent and acid-base reagents of pH-zone-refining.In this paper,the applications of different kinds of selective reagents in counter-current chromatography were summarized.The fundamental principle was introduced,and the way to improve the resolution was analyzed.Finally,the scope of application and the development trend of each selective reagents were also discussed. |
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