Discovery and Structure Identification of a New Phosphodiesterase-5 Inhibitor Derivative
  
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KeyWord:PDE-5 inhibitor analogue  UPLC-QTOF-MS  NMR  IR  structure identification
  
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MA Chun-yan,DUAN Qiong,FENG Shu-hua* 河北省药品检验研究院
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Abstract:
      One suspected phosphodiesterase-5 inhibitor(PDE-5) derivative was found in a kind of medicinal liquor by UPLC-DAD-QTOF-MS.Sample purification was carried out by a preparative HPLC system,and its structure was determined by NMR,IR and UPLC-DAD-QTOF-MS methods.The results showed that the compound is a new aildenafil derivative which has never been reported at home and abroad.
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