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| Progress in Research of Combinatorial Peptide Ligand Libraries for Protein Enrichment |
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| DOI： |
| KeyWord:low-abundance proteins combinatorial peptide ligand library proteomics research progress review |
| Author | Institution |
| FAN Jiao-jiao,LI Su-ying,LI Chun-hong,CHEN Hua,XIA Zhi-ning,YANG Feng-qing* |
1.重庆大学化学化工学院;2.河南医学高等专科学校药学系 |
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| Abstract: |
| The low-abundance proteins play an important role in the biological activity of living organisms,involving in many physiological or pathological processes,such as metabolism,transcription and translation.Therefore,the analysis and identification of low-abundance proteins are vital in the study of proteomics.Combinatorial peptide ligand library(CPLL) is an effective method for the enrichment of low-abundance proteins,and the detection and identification of low-abundance proteins could be achieved after treated by CPLL.According to studies on the CPLL reported in recent years,its applications in different fields including the studies on low-abundance proteins in human,animal and plant protein samples were reviewed.The main purpose of this review is to provide a reference for future researches and applications of CPLL. |
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