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| Research on Aptasensor Development for Estrogen Detection |
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| DOI： |
| KeyWord:estrogen aptamer colorimetry fluorescence electrochemistry review |
| Author | Institution |
| ZHANG Gui-lan，ZHU Chao，HUANG Ya-fei，YAN Jiao，CHEN Ai-liang |
中国农业科学院农业质量标准与检测技术研究所 |
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| Abstract: |
| Estrogen is a kind of steroid hormone，belonging to endocrine disruptors，which seriously interfere with the normal endocrine function of human and wildlife.Therefore，it is quite necessary to develop a simple and rapid method for the sensitive determination of estrogen present in the environment to protect public and environment health.Aptamers are selected in vitro by systematic evolution of ligands by exponential enrichment（SELEX），and are single stranded DNA or RNA molecules that can bind to various targets with high sensitivity and specificity.Aptamer has been widely used in analysis field because of its several overwhelming advantages over antibodies，such as target diversity，high stability，easy of synthesis and modification for applications.In this review，the researches on estrogen aptamer selection and aptamer based detection methods were summaried，and the development trend of aptasensor application in estrogen detection was also discussed. |
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