|
| Development and Characterization of LC-MS Interface Technology |
| |
| View Full Text Download reader |
| DOI： |
| KeyWord:LC-MS interface technology atmospheric pressure interface ion source |
| Author | Institution |
| TIAN Qin-qin,ZHU Hui,HUANG Zheng-xu,HUANG Bao,ZOU Xing,LIN Li-quan,LI Hui4,YIN Chen |
1.暨南大学质谱仪器与大气环境研究所;2.昆山禾信质谱技术有限公司;3.广东省大气污染在线源解析系统工程技术研究中心;4.广州禾信仪器股份有限公司 |
|
| Hits: 1849 |
| Download times: 838 |
| Abstract: |
| A homemade LC-MS interface was developed.The interface included atmospheric interface,ion source and electronic communication interface which connected to high-performance liquid chromatography and mass spectrometry′s software.The team self-developed API-TOFMS 10000 was successfully linked to Thermo Fisher Scientific Diana U3000.Experimental results showed that the self-built LC-MS was operated with a good stability(RSD=5.6%),the linear correlation coefficient(r2) was 0.995 8,the detection range: 2-2 000 pg,the limit of quantitation: 2 pg,and the detection limit: 0.5 pg.Piroxicam,theophylline and prednisone could be obviously detected.The experimental data showed that the self-developed LC-MS interface could meet the testing requirements,and the self-built LC-MS has an application potential in biochemistry,pharmaceutical analysis,food safety,environmental detection etc. |
| Close |
|
|
|