|
| Scientific PapersSynthesis of Nitrogen-doped Carbon Quantum Dots and Their Applications in Cellular Imaging and o-Nitrophenol Detection |
| |
| View Full Text Download reader |
| DOI： |
| KeyWord:nitrogen doped carbon quantum dots cellular imaging hydrothermal method o-nitrophenol(o-NP) water fluorescence quenching |
| Author | Institution |
| JIANG Li,LIANG Jun-yi,WANG Yu-tong,BAO Lin-chun,WU Yun,ZHENG Yu-guo,XIA Guang-ping,ZHANG Xiao-lan,ZHANG Qian-chun |
1.School of Biology and Chemistry,Xingyi Normal University for Nationalities;2.Key Laboratory of Chemical Synthesis and Environmental Pollution Control-Remediation Technology of Guizhou Province;3.Clinical Laboratory,Qian Xi Nan People's Hospital |
|
| Hits: 1566 |
| Download times: 970 |
| Abstract: |
| A kind of nitrogen doped carbon quantum dots(N-CQDs),with economy,low toxicity and even strong fluorescence performance,were successfully synthesized by hydrothermal method using L citrulline and urea as precursors.The performance of N-CQDs was characterized by transmission electron microscopy(TEM),Fourier transform infrared spectroscopy(FT-IR) and X-ray photoelectron spectroscopy(XPS),etc.Results showed that the quantum yield of the N-CQDs reached up to 39.2% with an average particle size of 2.8 nm,which could be used for HepG2 cell imaging in view of their good water solubility,stability and biocompatibility.In addition,a fluorescence probe with high selectivity and sensitivity was proposed for the detection of o-nitrophenol(o-NP) based on an experimental phenomenon that the fluorescence of the CQDs could be specifically quenched by o-NP.Results showed that there was a good linear relationship for o-NP in the range of 0.083 3-12.0 μmol/L with a correlation coefficient(r2) of 0.998 and a detection limit(LOD) of 25.2 nmol/L(S/N=3).The proposed method was successfully applied in the detection of o-NP in real water samples from Wanfeng Lake and Dingxiao River in Guizhou province. |
| Close |
|
|
|