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| Advances on Application of Rolling Circle Amplification-mediated Nucleic Acid Signal Amplification Strategy in Biosensors |
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| DOI： |
| KeyWord:isothermal nucleic acid amplification rolling circle amplification biosensor |
| Author | Institution |
| LIU Ju,LIANG Tao-bo,XU Heng-yi |
State Key Laboratory of Food Science and Technology,Nanchang University |
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| Abstract: |
| Rolling circle amplification(RCA) is an isothermal nucleic acid amplification technique.Due to its high efficiency and high fidelity,this technique has been widely used in biosensors.This review introduces the principle of RCA technique,the common cyclization types of RCA template and the common types of RCA,as well as the fluorescent,colorimetric and electrochemical biosensors based on RCA.The aim of this review is to provide references for the further development and application of the RCA technique in biosensors. |
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