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| Determination of Iminoctadine Residues in Fruits and Vegetables by Solid Phase Extraction and Liquid Chromatography－ Tandem Mass Spectrometry |
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| DOI： |
| KeyWord:iminoctadine ?iminoctadine tris（albesilate） ?citrus ?solid phase extraction ?liquid chromatography－tandem mass spectrometry |
| Author | Institution |
| QIN Fu，WANG Wen-long，SI Lu-lu，CAI Xiang-yu，LIANG Yu，SU Hua，WEI Tao |
Technical Center of Nanning Customs District，Nanning ，China |
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| Abstract: |
| A solid phase extraction and liquid chromatography－tandem mass spectrometry was developed for the determination of iminoctadine residues in fruits and vegetables including citrus，jackfruit，apple，grape，lettuce，cucumber，tomato and asparagu．Samples were extracted with 0.2% acetic acid，and preliminarily purified with dichloromethane. The extract solution was purified using a WCX solid phase extraction column，and the target compound was eluted with 10% formic acid acetonitrile．The eluent was blown to near dryness with nitrogen，and then redissolved with 0.2% formic water．The compound was separated on a C18 column with methanol and 0.2% formic acid water as mobile phases．The double charges additive ion m/z?178.8 and its daughter ions?m/z?100.0 and 187.0 from iminoctadine were selected for the multi reaction monitoring（MRM） scanning under the positive ion mode of electrospray ion source（ESI+）．The iminoctadine in the samples was quantified by the calibration curve of matrix addition standard．The correlation coefficients（r） were not less than 0.995，which indicated that the linear dependence of iminoctadine was good in the range of 0.005－0.160 mg/kg．The limits of detection（LOD） and quantitation（LOQ） for iminoctadine were 0.005 mg/kg and 0.010 mg/kg，respectively．The average recoveries at spiked levels of 0.010，0.020 and 0.050 mg/kg ranged from 88.5% to 109%，with the relative standard deviations（RSDs，n?= 6） of 2.1%－8.8%．With the advantages of rapidness，accuracy and sensitivity，this method is suitable for the determination of iminoctadine in fruits and vegetables． |
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