Research Progress on Detection of Pesticide Residues in Food by High-resolution Mass Spectrometry
  
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KeyWord:high-resolution mass spectrometry(HRMS)  food  pesticide residues  high-throughput detection
  
AuthorInstitution
ZHANG Shen-ping,ZHOU Jing,DU Ru-yun,ZHENG Yi,LIU Yang,XU Hong-bin Shanghai Institute of Quality Inspection and Technical Research/Key Laboratory of Milk and Dairy Products Detection and Monitoring Technology for State Market Regulation, Shanghai , China
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Abstract:
      It is of great significance to use accurate and reliable chromatography-mass spectrometry to screen and detect residues of pesticides,veterinary drugs,organic pollutants and other harmful substances in edible agricultural products.High-resolution mass spectrometry(HRMS) has higher resolution and accuracy quality in qualitative and quantitative detection on trace compounds in the complex food matrix.The technical characteristics of quadrupole/time-of-flight mass spectrometry(Q/TOF MS) and quadrupole/orbitrap mass spectrometry(Q/Orbitrap MS) are reviewed in this paper,and the applications of HRMS in detection of pesticide residues in plant and animal derived food at home and abroad from 2017 to 2022 are focused on. The development prospect of HRMS technology is discussed from three aspects,i.e. the development of HRMS technology,the technical requirements of food safety supervision departments and the third party testing institutions.In conclusion,chromatography-mass spectrometry has become the mainstream technology adopted in the national food safety standards in China since the early 21st century.The development and improvement of nanoflow-chromatography,heated dual ion source(DUIS) and other technologies are expected to improve the sensitivity of HRMS.The HRMS screening combined with triple quadrupole mass spectrometry confirmation technology,application and standardization of HRMS methods are the main directions for future research.
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